OPERANT SELF-MEDICATION FOR ASSESSMENT OF SPONTANEOUS PAIN RELIEF AND DRUG ABUSE LIABILITY IN MOUSE MODELS OF CHRONIC PAIN

Operant Self-medication for Assessment of Spontaneous Pain Relief and Drug Abuse Liability in Mouse Models of Chronic Pain

The search for safe and efficient chronic pain treatments is dampened by Air Tools the lack of reliable models that faithfully reproduce current pharmacological treatments for chronic spontaneous pain in humans.Preclinical models often assess the antinociceptive efficacy of non-contingent pharmacological treatments evaluated in the short-term.Here,

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Management of peritoneal dialysis related infections

Introduction: Patients with end-stage renal disease who start active treatment with peritoneal dialysis have an increased risk of developing infections.Methods: This paper will present information from relevant professional/scientific sources regarding modern diagnostic and therapeutic modalities for the treatment of infections in patients on perit

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Low-Intensity Focused Ultrasound Stimulation on Fingertip Can Evoke Fine Tactile Sensations and Different Local Hemodynamic Responses

Low-intensity focused ultrasound stimulation (LIFUS) has been proved effective in eliciting vibrotactile in addition to warm, cold and nociceptive pain when applied to human peripheral endings.However, if it can evoke fine tactile sensations has been rarely Air Tools investigated by far despite the importance of fine tactile feedback in motor contr

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